We are a global innovation-driven biopharmaceutical company specialising in the discovery, development, manufacturing and marketing of prescription medicines that make a meaningful difference in healthcare. Science and patients are at the heart of everything we do, and our skills and resources are concentrated on those therapy areas where we believe we can make the most difference. We focus primarily on cancer, cardiovascular/metabolic disease and respiratory/inflammation/autoimmunity. Alongside this, we remain active in infection and neuroscience with targeted investments in opportunities and collaborations.

Research Grants 845 show all


$82M
2016

$158.8M
2017

$103.2M
2018

$237.2M
2019

$3.7M
2020

Publications 35 show all

  • 11
    Adenosine/analogs & derivatives
  • 8
    Platelet Aggregation Inhibitors/therapeutic use
  • 7
    Acute Coronary Syndrome/drug therapy
  • 6
    Ticlopidine/analogs & derivatives
  • 4
    Purinergic P2Y Receptor Antagonists/therapeutic use
  • 3
    Stroke/prevention & control
  • 2
    Acute Coronary Syndrome/blood
  • 2
    Acute Coronary Syndrome/therapy
  • 2
    Diabetes Mellitus, Type 2/drug therapy
  • 2
    Growth Differentiation Factor 15/blood

Patents 32,975show all

  • 12,227
    C07D - Heterocyclic compounds
  • 5,802
    A61K - Preparations for medical, dental, or toilet purposes
  • 1,850
    C07C - Acyclic or carbocyclic compounds
  • 794
    A61M - Devices for introducing media into, or onto, the body
  • 682
    C07K - Peptides
  • 472
    C07F - Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
  • 380
    Y02P - Climate change mitigation technologies in the production or processing of goods
  • 375
    G01N - Investigating or analysing materials by determining their chemical or physical properties
  • 369
    C07B - General methods of organic chemistry
  • 278
    C12Q - Measuring or testing processes involving enzymes, nucleic acids or microorganisms

Clinical Trials 5,737show all

1,464Phase 31,212N/A919Phase 2862Phase 1362Phase 4174Other

Contact Information

Wilmington, DE
United States