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Patent
Publication NumberUS 8809344Filing StatusIssued PatentAvailabilityUnknownFiling Date2009-10-29Publication Date2014-08-19
Various tetrahydropyrazolo[1,5-a]pyrimidine compounds, compositions, methods of making, and methods for the prevention and treatment of HCV infections and associated diseases are disclosed. The invention further relates to biomarkers for identification of HCV strains which are resistant to the tetrahydropyrazolo[1,5-a]pyrimidine compounds.
Patent
Publication NumberAT 555208 TFiling StatusOtherAvailabilityUnknownFiling Date2004-06-14Publication Date2012-05-15
Patent
Publication NumberEP 1636371 B1Filing StatusIssued PatentAvailabilityUnknownFiling Date2004-06-14Publication Date2012-04-25
Patent
Publication NumberCA 2544847 CFiling StatusIssued PatentAvailabilityUnknownFiling Date2004-10-22Publication Date2012-01-31
Patent
Publication NumberUS 7807345Filing StatusIssued PatentAvailabilityUnknownFiling Date2007-08-02Publication Date2010-10-05
The present invention provides compositions and methods for the detection of the presence, absence, or quantity of a segmented negative strand RNA virus such as an influenza virus. A genetically engineered vertebrate cell comprising an artificial segment comprising a 5′ UTR and a 3′ UTR of a segmented negative strand RNA virus and an open reading frame of a reporter gene, preferably in an anti-sense orientation, is contacted with a biological specimen suspected of comprising a segmented negat…
Patent
Publication NumberWO 2010096115 A1Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2009-10-29Publication Date2010-08-26
Various tetrahydropyrazolo[1,5-a]pyrimidine compounds, compositions, methods of making, and methods for the prevention and treatment of HCV infections and associated diseases are disclosed. The invention further relates to biomarkers for identification of HCV strains which are resistant to the tetrahydropyrazolo[1,5- a]pyrimidine compounds.
Patent
Publication NumberUS 7585667Filing StatusIssued PatentAvailabilityUnknownFiling Date2004-06-14Publication Date2009-09-08
The present invention relates to non-cytopathic negative-strand RNA virus replicons, and methods of making and using the replicons and replicon systems.
Research Grant
Project Number5U01AI075424-02Funding AgencyNational Institutes of HealthEffective Date2008-09-01Expiration Date2009-08-31Funding Amount$712,161
[unreadable] DESCRIPTION (provided by applicant): [unreadable] Currently, there is no specific antiviral therapy available for the treatment of flavivirus infections, including West Nile Virus (WNV), a Biodefense Category B agent. Therefore, the development of novel classes of antiviral agents is of high priority for public health and defense against a possible bioterrorism attack. For this initiative, our goal is to develop small molecule inhibitors of WNV. In our preliminary experiments, we…
Patent
Publication NumberAU 2003210675 B2Filing StatusIssued PatentAvailabilityUnknownFiling Date2003-01-28Publication Date2008-05-29
Methods and compositions are provided for screening candidate antiviral agents using cells containing subgenomic viral replication systems such as replicons and minigenomes. The methods involve the simultaneous assay of more than one subgenomic viral replication system. Compositions useful for these methods are also provided.
Patent
Publication NumberEP 1877055 A2Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2006-05-04Publication Date2008-01-16
We found 51 documents that match your Search
Research Grants: 30
Patents: 21

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