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Publication
ID32520986Published Date2020-08-03JournalThe Journal of cell biology, 2020-08-03, Volume 219
Stress granules are dynamic assemblies of proteins and nontranslating RNAs that form when translation is inhibited in response to diverse stresses. Defects in ubiquitin-proteasome system factors including valosin-containing protein (VCP) and the proteasome impact the kinetics of stress granule induction and dissolution as well as being implicated in neuropathogenesis. However, the impacts of dysregulated proteostasis on mRNA regulation and stress granules are not well understood. Using single…
Stephanie L Moon Tatsuya Morisaki Timothy J Stasevich Roy Parker
University of MichiganUniversity of MichiganColorado State UniversityColorado State UniversityUniversity of ColoradoUniversity of Colorado
Publication
IDDOI:10.1146/annurev-economics-091619-032800Published Date2020-08-02JournalAnnual Review of Economics, 2020-08-02, Volume 12
The issue of one's identity has loomed large recently and has unfortunately been used more and more as a wedge to separate subgroups. It is important to understand the ramifications of identity, both to limit the negative consequences (such as so-called identity politics) and to be able to use one's sense of identity as a positive force in the world. What are effective approaches to allow positive identities and pride about one's social identity to be reinforced for the greater good? Recent w…
Gary Charness Yan Chen
University of California, Santa BarbaraUniversity of California, Santa BarbaraUniversity of California SystemUniversity of California SystemUniversity of MichiganUniversity of MichiganTsinghua UniversityTsinghua University
Publication
ID26218314Published Date2020-08-02JournalCancer biology & therapy, 2020-08-02, Volume 21
Epithelial-Mesenchymal Transition (EMT) and angiogenesis are crucial events for development of aggressive and often fatal Oral Squamous Cell Carcinomas (OSCCs). Both blood vessel neo-formation and contribute to OSCC cell growth, tumor mass development, and dissemination. has an important role, not only in angiogenic mechanisms, but also in favoring cancer invasion. Indeed it decreases the expression of E-cadherin and leads to phenotypic changes in epithelial cells (EMT) enhancing their carcin…
Angela Santoro Pantaleo Bufo Giuseppe Russo Simona Cagiano Silvana Papagerakisshow 8 more
University of FoggiaUniversity of FoggiaUniversity of MichiganUniversity of MichiganNational Cancer Institute (NCI)National Cancer Institute (NCI)National Institutes of Health (NIH)National Institutes of Health (NIH)United States Department of Health and Human Services (HHS)United States Department of Health and Human Services (HHS)show 1 more
Publication
ID30527631Published Date2020-08-01JournalCytokine, 2020-08-01, Volume 132
Type I interferons (IFNs) are an immunomodulatory class of cytokines that serve to protect against viral and bacterial infection. In addition, mounting evidence suggests IFNs, particularly type I but also IFNγ, are important to the pathogenesis of autoimmune and inflammatory skin diseases, such as cutaneous lupus erythematosus (CLE). Understanding the role of IFNs is relevant to anti-viral responses in the skin, skin biology, and therapeutics for these IFN-related conditions. Type I IFNs (α a…
Publication
ID32445948Published Date2020-08-01JournalEnvironmental research, 2020-08-01, Volume 187
Flocculant overdose has been considered an inefficient technique for precipitating heavy metals from wastewater at low levels due to the high yield of hazardous waste sludge that should be treated properly before it can be disposed of safely in landfills. This problem was effectively solved in this study via a novel method that recycles sludge separately into high-purity hematite and heavy metal-bearing products. The wastewater, which contained 10.3 mg/L of Co and 4.8 mg/L of Sr, was coagulat…
Ting Su Zhijie Han Zhan Qu Chen Yu Xue Linshow 3 more
Northeast Normal UniversityNortheast Normal UniversityMichigan Technological UniversityMichigan Technological University
Publication
ID32505825Published Date2020-08-01JournalUltramicroscopy, 2020-08-01, Volume 215
The technique of atom probe tomography is often used to image solute clusters and solute atom segregation to dislocation lines in structural alloys. Quantitative analysis, however, remains a common challenge. To address this gap, we combined a cluster finding algorithm, a skeleton finder algorithm, and morphological classification of dense objects to distinguish solute clusters from solute-decorated dislocation lines, both being characterized by high solute atom densities. The proposed workfl…
Publication
ID32650927Published Date2020-08-01JournalThe American journal of cardiology, 2020-08-01, Volume 128
We obtained directly measured maximal oxygen uptake (VO max) by open-circuit spirometry in 1,453 patients with chronic heart failure (HF) who completed a treadmill test (n = 1,453) or cycle ergometry (n = 1,838), as participants in The Fitness Registry and the Importance of Exercise National Data Base (FRIEND) dataset. We developed a new equation to predict measured VO max in those using a treadmill by randomly sampling 70% of the participants from each of the following age categories:
Peter Kokkinos Leonard A Kaminsky Ross Arena Jiajia Zhang Barry Franklinshow 5 more
University of South Carolina, ColumbiaUniversity of South Carolina, ColumbiaU.S. Department of Veterans AffairsU.S. Department of Veterans AffairsRutgers UniversityRutgers UniversityBall State UniversityBall State UniversityUniversity of Illinois at ChicagoUniversity of Illinois at Chicagoshow 6 more
Publication
IDDOI:10.1115/1.4046477Published Date2020-08-01JournalJournal of Dynamic Systems, Measurement, and Control, 2020-08-01, Volume 142
Abstract Widely published research shows that significant fuel economy improvements through optimal control of a vehicle powertrain are possible if the future vehicle velocity is known and real-time optimization calculations can be performed. In this research, however, we seek to advance the field of optimal powertrain control by limiting future vehicle operation knowledge and using no real-time optimization calculations. We have realized optimal control of acceleration events (AEs) in real-t…
Zachary D Asher David A Trinko Joshua D Payne Benjamin M Geller Thomas Bradley
Western Michigan UniversityWestern Michigan UniversityColorado State UniversityColorado State University
Publication
IDDOI:10.1177/1948550619878423Published Date2020-08-01JournalSocial Psychological and Personality Science, 2020-08-01, Volume 11
Research suggests that change goals (desires to change personality traits) predict subsequent trait growth. In this article, we (re)analyzed all data our labs have collected as of May 2019 that included measures of change goals and repeated measures of personality traits (12 studies; total n = 2,238). Results indicated that change goals robustly predicted growth in all five traits. Effect sizes were largest for extraversion and emotional stability (people with high change goals were predicted…
Nathan W Hudson R Chris Fraley William J Chopik Daniel A Briley
Southern Methodist UniversitySouthern Methodist UniversityUniversity of Illinois at Urbana-ChampaignUniversity of Illinois at Urbana-ChampaignMichigan State UniversityMichigan State University
Publication
ID32500541Published Date2020-08-01JournalNMR in biomedicine, 2020-08-01, Volume 33
This study introduces a technique called cine magnetic resonance fingerprinting (cine-MRF) for simultaneous T , T and ejection fraction (EF) quantification. Data acquired with a free-running MRF sequence are retrospectively sorted into different cardiac phases using an external electrocardiogram (ECG) signal. A low-rank reconstruction with a finite difference sparsity constraint along the cardiac motion dimension yields images resolved by cardiac phase. To improve SNR and precision in the par…
Jesse I Hamilton Yun Jiang Brendan L Eck Mark Griswold Nicole Seiberlich
University of MichiganUniversity of MichiganCase Western Reserve UniversityCase Western Reserve University
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