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Patent
Publication NumberUS 10463609Filing StatusIssued PatentAvailabilityUnknownFiling Date2008-10-06Publication Date2019-11-05
Dendrimer-based compositions and methods are provided, that are useful for administering pharmaceutical compositions to target cells and tissues for treatment of ocular diseases including macular degeneration, diabetic retinopathy, and retinitis pigmentosa.
Patent
Publication NumberUS 10467924Filing StatusIssued PatentAvailabilityUnknownFiling Date2013-09-20Publication Date2019-11-05
A computer-implemented tool having a collection of content management subsystems allows the content creator to construct a web-based behavioral modification site without the need for computer programming skills. The content delivery system constructed with this tool employs a lesson manager that delivers lesson content based on a tree structure; a virtual educator manager that presents different graphical images of an educator character, complete with different facial expressions and gestures…
Patent
Publication NumberUS 10463864Filing StatusIssued PatentAvailabilityUnknownFiling Date2016-09-14Publication Date2019-11-05
An energy harvester having a plurality of bimorph beams and a plurality of piezoelectric devices, wherein at least two of the piezoelectric devices are mounted to each of the plurality of bimorph beams. A plurality of rigid beams interconnect adjacent ends of the bimorph beams to define a stacked, fan-folded shape having a first end of one of the bimorph beams mounted to a structure. A tip mass is disposed on a free end of another of the plurality of bimorph beams. Upon movement of the energy…
University of MichiganUniversity of MichiganResearch Foundation for SUNYResearch Foundation for SUNY
Patent
Publication NumberUS 10463734Filing StatusIssued PatentAvailabilityUnknownFiling Date2015-04-24Publication Date2019-11-05
Nanoparticles comprising a metal oxide and a platinum cluster having a height to base ratio greater than 1 and compositions containing the same are disclosed. Methods of using the nanoparticles in producing hydroxyl radicals and in photodynamic therapy, for example, in the treatment of hyperproliferative disease such cancer, are also disclosed.
Patent
Publication NumberUS 10463314Filing StatusIssued PatentAvailabilityUnknownFiling Date2018-07-19Publication Date2019-11-05
Systems and methods for predicting and/or detecting cardiac events based on real-time biomedical signals are discussed herein. In various embodiments, a machine learning algorithm may be utilized to predict and/or detect one or more medical conditions based on obtained biomedical signals. For example, the systems and methods described herein may utilize ECG signals to predict and detect cardiac events. In various embodiments, patterns identified within a signal may be assigned letters (i.e., …
Patent
Publication NumberUS 10465091Filing StatusIssued PatentAvailabilityUnknownFiling Date2016-04-27Publication Date2019-11-05
Durable icephobic materials form anti-ice coatings on a variety of substrates, including for aircraft, powerlines, vehicles, marine structures, communications towers, outdoor equipment, and the like. The icephobic may comprise an elastomeric polymer with a low crosslink density (e.g., ≤1,300 mol/m3) and low initial ice adhesion strength (e.g., τice≤100 kPa prior to exposure to icing conditions). Further, the icephobic material maintains τice after 10 icing/deicing cycles that is ≥50% of the i…
Patent
Publication NumberUS 10466287Filing StatusIssued PatentAvailabilityUnknownFiling Date2017-05-15Publication Date2019-11-05
An inductive-capacitive (LC) wireless sensor for the detection of toxic heavy metal ions includes inductors and interdigitated electrodes (IDE) in planar form. The sensor is fabricated by screen printing silver (Ag) ink onto a flexible polyethylene-terephthalate (PET) substrate to form a metallization layer. Palladium nanoparticles (Pd NP) is drop casted onto the IDEs to form a sensing layer. The resonant frequency of the LC sensor is remotely monitored by measuring the reflection coefficient…
Patent
Publication NumberUS 20190328930Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2019-04-30Publication Date2019-10-31
Provided is a bioink comprising a mixture comprising a collagen and a polysaccharide, and a polyhedral oligomeric silsesquioxane (POSS), a hydrogel matrix formed from a bioink comprising a mixture comprising a collagen and a polysaccharide, and a polyhedral oligomeric silsesquioxane (POSS), a 3D biomaterial scaffold comprising a hydrogel matrix of the disclosure as a first hydrogel layer and a hydrogel matrix of the disclosure as a second hydrogel layer, optionally having an intervening layer…
Patent
Publication NumberUS 20190330653Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2017-08-25Publication Date2019-10-31
Plants, plant cells, and seeds are described herein that grow well and are resistant to environmental stresses such as drought and insects, where the plants have one or more mutations that reduce or eliminate the interaction of MYC transcription factors with the JAZ proteins. The plants can have an additional mutation that reduces or eliminates the function of the PHYB gene, and/or a heterologous PIF4 transgene or PIF4 expression cassette to improve the growth of the myc mutant plants. Method…
Patent
Publication NumberUS 20190328835Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2016-12-16Publication Date2019-10-31
The present invention relates to the field of (bio-)medicine, and more particularly to the treatment of copper-related diseases. Novel means and methods for depleting (excess) copper from organs and/or the circulation are provided. Agents with a high copper binding affinity and stabilized forms thereof are provided, as well as a novel treatment regimen. The means and methods of the present invention are particularly useful for treatment of Wilson Disease, but also for treatment of other condi…
University of MichiganUniversity of MichiganIowa State UniversityIowa State UniversityHelmholtz Zentrum Munchen Deutsches Forschungszentrum fur Gesundheit und Umwelt (GmbH)Helmholtz Zentrum Munchen Deutsches Forschungszentrum fur Gesundheit und Umwelt (GmbH)