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Opportunity
IDFBX2:8645Post Date2020-03-20
The CDC estimates that the Autism incidence rate in children has increased from 1:68 to 1:59 in just the past two years. Additionally, up to 95% of kids with autism experience sensory modulation comorbidities. A critical part of social behavior is the ability to process, perform and interpret a vast repertoire of motor actions, and having a restricted selection of movement skills means fewer opportunities for social interaction and ultimately degraded social outcomes in affected youth.
Opportunity
IDFBX2:8642Post Date2020-03-18
The technology disclosed is a Luria-Delbruck fluctuation test for influenza virus mutation rates that scores reversion to fluorescence in a set of 12 mutant green fluorescent proteins (GFP). Globally, seasonal influenza is a major cause of severe respiratory infections, leading to excessive hospitalizations and 1 million deaths/year. The global influenza market (vaccines, antivirals, and diagnostic products)grew from ~$3.8 billion in 2012 to ~$4 billion in 2013. Sales for influenza…
Opportunity
IDFBX2:8641Post Date2020-03-18
xflow is a discontinuous Galerkin finite element software library for computational fluid dynamics. It supports one, two, and three-dimensional simulations in space, and numerous time advancement schemes. Various dynamically-loaded equation sets are supported, including compressible Navier-Stokes, scalar convection/ diffusion/ reaction, acoustics, and shallow-water equations. Supported discretizations include traditional discontinuous Galerkin as well as hybridized versions (HD…
Opportunity
IDFBX2:8637Post Date2020-03-16
This technology consists of a novel method for treating human mesenchymal stem cells (hMSCs) with IFN-γto increase immunomodulatory function. Unlike previous methods, this technology allows researchers to treat hMSCs in vivo by tethering IFN-γto a hydrogel scaffold surrounding the cells. Because this is an in vivo method as opposed to ex vivo, regulation restrictions are not as pertinent and this therapy will be easier to apply.
Opportunity
IDFBX2:8638Post Date2020-03-16
This technology consists of a novel method to purify proteins onto a cryo-EM grid. Unlike other methods which require first purifying protein and then preparing the grid, this technique utilizes an antibody-based graphene system to purify proteins directly onto the grid. Using this method, there is not wasted protein and much smaller quantities can be used, making in vivo purification possible.
Opportunity
Track Code8609Post Date2020-03-10TypeAvailable Technology
Accurate intracranial pressure (ICP) monitoring is essential for evaluating and treating traumatic brain injuries (TBIs). There is also evidence that ICP monitoring after primary decompressive craniectomy for TBI patients may significantly decrease in-hospital mortality. During the hours immediately after TBI and especially in rapidly changing environments with limited resources, such as patient transport or field hospitals, the ability to not only measure ICP, but also quantify and regula…
Opportunity
Track Code8608Post Date2020-03-10TypeAvailable Technology
The NIH estimates that 50 to 70 million people in the US alone have chronic sleep disorders and obstructive sleep apnea (OSA). Sleep disorders are associated with a number of serious health risks, including heart disease, high blood pressure, and diabetes. Due to a lack of awareness and costly and unpleasant testing procedures, the majority of sleep problems remain undiagnosed and untreated. An inexpensive way to diagnose sleep disorder is to monitor the salivary levels of melatonin…
Opportunity
Track Code8605Post Date2020-03-10TypeAvailable Technology
In developing countries, about 215 million women have an unmet need for modern contraception. Subcutaneous contraceptive implants are one of the most effective forms of reversible long-term contraception. The implants are small polymer rods that gradually deliver etonogestrel over time, providing contraceptive protection for 3-5 years. The implants must be administered by mid- to high-level professionals due to the adverse complications that arise from improper insertion into fat or muscle…
Opportunity
Track Code8607Post Date2020-03-10TypeAvailable Technology
The amino acid cysteine, also called L-cysteine, is considered non-essential because we have the ability to produce it; however, there are many times, such as during infancy or with advanced age, that we do not produce enough cysteine to properly aid in metabolic functions. Additionally, people with metabolic diseases often suffer from inadequate amounts of cysteine. Cysteine production for use in dietary supplements or pharmaceuticals has consequently become a large market. To those ends,…
Opportunity
Track Code8606Post Date2020-03-10TypeAvailable Technology
An estimated 85 million people in the U.S. are living with a form of cardiovascular disease or the after-effects of a stroke and the incidence of hypertension, cardiac aneurysms, and coronary artery disease continues to increase. Vascular surgery to substitute damaged tissue requires grafts that are biologically responsive. Patient-derived autografts are the gold standard for vascular occlusion treatments, but they are not always adequate or suitable. Prosthetic grafts are widely used clin…