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Clinical Trial
Clinical Trial IDNCT03878147Start Date2019-08-01Completion Date2024-12-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
The investigators will use Brain Power Games, a computer-based learning game for children, as a neurocognitive "stress test" or medical "challenge" test, in order to evaluate brain/behavior functional integrity in HIV-affected children. This dual use of BPG is a key innovative feature. Each of the 5 core BPG games lasts 10 minutes and trains fine motor, monitoring/attention, visual/auditory working memory, spatial navigational learning. In Year 3 we'll add an Executive Functioning (EF) test t…
Clinical Trial
Clinical Trial IDNCT03928756Start Date2019-08-01Completion Date2019-09-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
The main aim of this formative study is to test and iteratively refine a new mobile phone app, which delivers assessments and tailored intervention content. The study will use social media advertisements to recruit a total of 40 youth between the ages of 16-24 years. Those screening positive for past-month binge drinking or marijuana use will be invited to complete a baseline survey, download and use the app for 30 days, and complete a follow-up survey about the app functionality, design and …
Clinical Trial
Clinical Trial IDNCT03763838Start Date2019-08-01Completion Date2021-10-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
The purpose of this study is to see if accupressure can help reduce the severity of fatigue experienced by ovarian cancer patients. Acupressure involves applying mild to moderate physical pressure by fingers, hand or a device to specific points on the skin to try to bring about a change in the body's functioning, in this case relief from chronic fatigue.
Clinical Trial
Clinical Trial IDNCT03978936Start Date2019-08-01Completion Date0001-02-27PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
Improving Medication Adherence with Telehealthcare Medication Therapy Management to Change Health Outcomes in Adolescents and Young Adults with Asthma (MATCH) is a multi-center, randomized parallel group study targeted to an at-risk population of Adolescents and Young Adults (AYA) with uncontrolled asthma who have poor adherence with prescribed Inhaled corticosteroid (ICS) therapy.
Kathryn V Blake Robert A Wise Janet Holbrook
University of Alabama BirminghamUniversity of Alabama BirminghamUniversity of ArizonaUniversity of ArizonaUniversity of California San Francisco (UCSF)University of California San Francisco (UCSF)University of California SystemUniversity of California SystemNational Jewish HealthNational Jewish Healthshow 15 more
Clinical Trial
Clinical Trial IDNCT03960827Start Date2019-08-01Completion Date2023-09-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
The goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity (PA). To achieve this aim, a mechanistic randomized controlled trial (RCT) is conducted, in which adult study participants are randomized to endurance exercise (EE) training, resistance exercise (RE) training, or no exercise Control for a period of approximately 12 weeks. The overarching hypothesis is that there are discoverable molecular t…
Marco Pahor
University of Alabama BirminghamUniversity of Alabama BirminghamUniversity of ColoradoUniversity of ColoradoBall State UniversityBall State UniversityPennington Biomedical Research CenterPennington Biomedical Research CenterDuke UniversityDuke Universityshow 15 more
Clinical Trial
Clinical Trial IDNCT03945552Start Date2019-07-01Completion Date0028-01-30PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
Public health disasters have disproportionate impacts on low income communities, through pathways that add to those of poverty and associated stressors, and act over extended periods. Very young children are highly vulnerable to long-term impacts on development and mental health in the context of parenting challenges following disasters, yet frequently receive the least attention and resources. This study will test the role of universal parenting support in enhancing young children's developm…
Alan Mendelsohn
New York UniversityNew York UniversityNational Institute of Child Health and Human Development (NICHD)National Institute of Child Health and Human Development (NICHD)National Institutes of Health (NIH)National Institutes of Health (NIH)United States Department of Health and Human Services (HHS)United States Department of Health and Human Services (HHS)Michigan State UniversityMichigan State Universityshow 2 more
Clinical Trial
Clinical Trial IDNCT03883165Start Date2019-07-01Completion Date2023-02-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
Sport-related concussion is a common and serious injury that can affect athletes of all ages in any sport. The purpose of this project is to study the effect of a 12-week manual resistance neck strengthening exercise program on participants' neck size and strength and how their heads and necks move during simulated sport-associated tasks. This study will help determine if greater neck strength may lower an athlete's risk of sport-related concussion. Each healthy male and female soccer athlete…
University of MichiganUniversity of MichiganNational Institute of Child Health and Human Development (NICHD)National Institute of Child Health and Human Development (NICHD)National Institutes of Health (NIH)National Institutes of Health (NIH)United States Department of Health and Human Services (HHS)United States Department of Health and Human Services (HHS)
Clinical Trial
Clinical Trial IDNCT03541889Start Date2019-07-01Completion Date2024-12-01Study TypeObservationalStatusNot yet recruiting
The primary objective is to evaluate whether an investigational nuclear medicine test (FLT imaging) distinguishes delayed engraftment from graft failure after hematopoietic stem cell transplantation (HSCT, which is when the patient's blood system is depleted and a new healthy blood system infused) and Objectives:Secondary: - Map the cellular pathway to subclinical (before the new cells are present in the blood) engraftment after cord blood and haplo-identical engraftment through FLT imaging, …
Kirsten Williams
Children's National Health SystemChildren's National Health SystemUniversity of MichiganUniversity of MichiganUniversity of OklahomaUniversity of Oklahoma
Clinical Trial
Clinical Trial IDNCT03632317Start Date2019-07-01Completion Date2025-09-01PhasePhase 2Study TypeInterventionalStatusRecruiting
This phase 2 trial will evaluate the activity of Panobinostat in combination with Everolimus for children with gliomas harboring H3.1 or H3.3K27M mutation, including newly diagnosed high-grade glioma or DIPG (diffuse intrinsic pontine glioma) after radiation (stratum A) and recurrent/progressive glioma (grade II-IV, including DIPG) (stratum B).
Clinical Trial
Clinical Trial IDNCT04016298Start Date2019-07-01Completion Date2020-02-01Study TypeObservationalStatusNot yet recruiting
The Prevention of Lower Urinary Symptoms (PLUS) Research Consortium is working to optimize prevention of lower urinary tract symptoms (LUTS) in women and adolescent females across their life spans. The ability to measure bladder health and key risk and protective factors is crucial to the PLUS mission. To describe and measure the spectrum of bladder health in diverse populations, researchers need a valid and reliable instrument. To date, the Consortium's work on design of a bladder health ins…
Melissa L Constantine Emily S Lukacz
University of MinnesotaUniversity of MinnesotaUniversity of California San Diego (UCSD)University of California San Diego (UCSD)University of California SystemUniversity of California SystemUniversity of PennsylvaniaUniversity of PennsylvaniaYale UniversityYale Universityshow 6 more
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