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Clinical Trial
Clinical Trial IDNCT03843021Start Date2019-04-01Completion Date2023-09-01Study TypeObservationalStatusNot yet recruiting
Annually, more than 250,000 patients in the U.S. with end-stage heart failure stand to benefit from ventricular assist device (VAD) therapy. 60% of patients develop a healthcare-associated infection (HAI) within 90-days of implantation. The investigators long term goal is to develop and subsequently promote wide-scale adoption of evidence-based HAI prevention practices following durable VAD implantation. This will be done by addressing the following aims: Aim 1. Identify determinants of cente…
Clinical Trial
Clinical Trial IDNCT03869905Start Date2019-04-01Completion Date2022-03-01PhasePhase 2Study TypeInterventionalStatusNot yet recruiting
The purpose of this study is to determine if Aquamin® works as a potential treatment to improve symptoms and if it will extend remission in patients with stable Ulcerative Colitis.
Clinical Trial
Clinical Trial IDNCT03739307Start Date2019-04-01Completion Date2023-03-01Study TypeObservationalStatusNot yet recruiting
This is a five year multi-site, cross sectional, observational study designed to examine chronic pain and pain treatment after moderate to severe TBI.
Cynthia Lee Harrison-Felix
Craig HospitalCraig HospitalUniversity of WashingtonUniversity of WashingtonSpaulding Rehabilitation HospitalSpaulding Rehabilitation HospitalWayne State UniversityWayne State UniversityMayo ClinicMayo Clinicshow 3 more
Clinical Trial
Clinical Trial IDNCT03607500Start Date2019-04-01Completion Date2020-07-01PhaseN/AStudy TypeInterventionalStatusRecruiting
One possible reason that weight gain after transplant may interfere with new kidney function is due to the enlargement of a kidney structure called the glomerulus. The researchers believe that modest caloric intake reduction (CIR) early after kidney transplantation can reduce the enlargement (hypertrophy) of the glomerulus associated with kidney transplantation and may improve long term allograft survival, by reducing glomerular hypertrophy mediated progressive glomerulosclerosis.
Clinical Trial
Clinical Trial IDNCT03634033Start Date2019-04-01Completion Date0031-08-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
Nearly half of older adults report problems with function, which can lead to difficulty with activities of daily living and nursing home placement. Thus, there is a need to implement evidence-based models of care to improve function and those factors that support function in older adults living in the community. One such model is Community Aging in Place, Advancing Better Living for Elders (CAPABLE), a person-centered, nurse and occupational therapy intervention supported by assistive devices…
Clinical Trial
Clinical Trial IDNCT03763838Start Date2019-04-01Completion Date2021-06-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
The purpose of this study is to see if accupressure can help reduce the severity of fatigue experienced by ovarian cancer patients. Acupressure involves applying mild to moderate physical pressure by fingers, hand or a device to specific points on the skin to try to bring about a change in the body's functioning, in this case relief from chronic fatigue.
Clinical Trial
Clinical Trial IDNCT03422718Start Date2019-04-01Completion Date2023-05-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
This study evaluates a health theory based mobile health behavioral intervention to reduce blood pressure (BP) among hypertensive patients evaluated in a community Emergency Department (ED) setting.
Hurley Medical CenterHurley Medical CenterUniversity of MichiganUniversity of MichiganNational Institutes of Health (NIH)National Institutes of Health (NIH)United States Department of Health and Human Services (HHS)United States Department of Health and Human Services (HHS)National Institute on Minority Health and Health Disparities (NIMHD)National Institute on Minority Health and Health Disparities (NIMHD)
Clinical Trial
Clinical Trial IDNCT03632317Start Date2019-03-01Completion Date2025-09-01PhasePhase 2Study TypeInterventionalStatusRecruiting
This phase 2 trial will evaluate the activity of Panobinostat in combination with Everolimus for children with gliomas harboring H3.1 or H3.3K27M mutation, including newly diagnosed high-grade glioma or DIPG (diffuse intrinsic pontine glioma) after radiation (stratum A) and recurrent/progressive glioma (grade II-IV, including DIPG) (stratum B).
Clinical Trial
Clinical Trial IDNCT03729271Start Date2019-03-01Completion Date2020-09-01PhasePhase 4Study TypeInterventionalStatusNot yet recruiting
The purpose of this study is to learn more about how to improve treatment of patients with diarrhea predominant Irritable Bowel Syndrome (IBS-D) symptoms.Included patients will be requested to answer online surveys and will undergo treatment with rifaximin. Hydrogen breath testing and biologic samples collection will also be completed during the study.
Clinical Trial
Clinical Trial IDNCT03381183Start Date2019-03-01Completion Date2021-03-01PhasePhase 1/Phase 2Study TypeInterventionalStatusNot yet recruiting
The purpose of this study is to see if the IRX-2 regimen, durvalumab, and tremelimumab will have a tolerable safety profile and will increase the intratumoral immune profile compared with the pretreatment tumors.
Christine H Chung Nabil F Saba
H. Lee Moffitt Cancer Center and Research InstituteH. Lee Moffitt Cancer Center and Research InstituteEmory UniversityEmory UniversityUniversity of MichiganUniversity of Michigan
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