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Clinical Trial
Clinical Trial IDNCT04052828Start Date2020-02-01Completion Date2024-01-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
This is a single site pilot trial to assess the feasibility and safety of treating severe CDH with Fetal Endoscopic Tracheal Occlusion with the Goldballoon Detachable Balloon (GOLDBAL2) along with the Delivery Microcatheter (BALTACCI-BDPE100) at Michigan Medicine. The study will enroll pregnant women that meet study criteria. Participants will have placement of FETO between gestational age at 27 weeks plus 0 days and 29 weeks 6 days. The timing for removal of FETO will ideally be between 34 w…
Clinical Trial
Clinical Trial IDNCT04125680Start Date2020-01-01Completion Date2020-09-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
This research is using a Community-Based Participatory Action Research (CBPAR) approach to design, implement, and evaluate English as a Second Language health literacy classes for Hispanic adults to reduce lead exposure.
Clinical Trial
Clinical Trial IDNCT04157296Start Date2020-01-01Completion Date2021-01-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
This study will assign eighteen participants with anxiety to cognitive behavioral therapy (CBT) with computerized cognitive training (CCT). In addition, the study will have a control group and enroll thirty-six age- and gender-matched anxious children assigned to CBT. The hypothesis of this trial is that CCT with CBT will further increase task control network (TCN) activation and connectivity. Both groups will have one CBT therapy session each week for 12 weeks. However, for participants in t…
University of MichiganUniversity of MichiganNational Institutes of Health (NIH)National Institutes of Health (NIH)United States Department of Health and Human Services (HHS)United States Department of Health and Human Services (HHS)
Clinical Trial
Clinical Trial IDNCT03940716Start Date2020-01-01Completion Date0030-03-30PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
This study will use a randomized control trial design (RCT) to pilot test a multisession remote therapy behavioral intervention for risky firearm behaviors and associated behaviors/consequences among adolescents. The study will pilot a state-of-the-art intervention delivery approaches (e.g., remote therapy, smartphone-based APP intervention content delivery) for reducing violence and associated behaviors among urban youth. Given the significant morality and mortality associated with firearm v…
University of MichiganUniversity of MichiganNational Institute on Drug Abuse (NIDA)National Institute on Drug Abuse (NIDA)National Institutes of Health (NIH)National Institutes of Health (NIH)United States Department of Health and Human Services (HHS)United States Department of Health and Human Services (HHS)
Clinical Trial
Clinical Trial IDNCT04181138Start Date2020-01-01Completion Date2024-05-01Study TypeObservationalStatusNot yet recruiting
Primary sclerosing cholangitis (PSC) is a rare liver disease that damages the liver's bile ducts. Bile ducts are tiny tubes that carry bile from the liver to the small intestine. Bile is a liquid produced by the liver that helps us absorb and use the nutrients in the food we eat. In people with PSC, the bile backs up into the liver and will damage it, causing scarring of the liver. The purposes of this study are to: - Collect medical and other data to learn more about PSC, how it progresses, …
Cara Mack Ed Doo Averell Sherker John Magee Robert M Merionshow 15 more
Children's Hospital Los AngelesChildren's Hospital Los AngelesUniversity of California San Francisco (UCSF)University of California San Francisco (UCSF)University of California SystemUniversity of California SystemChildren’s Hospital ColoradoChildren’s Hospital ColoradoChildren's Healthcare Of AtlantaChildren's Healthcare Of Atlantashow 11 more
Clinical Trial
Clinical Trial IDNCT04137107Start Date2020-01-01Completion Date2025-12-01PhasePhase 2/Phase 3Study TypeInterventionalStatusNot yet recruiting
This phase II/III trial studies the best dose of duloxetine and how well it works in preventing pain, tingling, and numbness (peripheral neuropathy) caused by treatment with oxaliplatin in patients with stage II-III colorectal cancer. Duloxetine increases the amount of certain chemicals in the brain that help relieve depression and pain. Giving duloxetine in patients undergoing treatment with oxaliplatin for colorectal cancer may help prevent peripheral neuropathy.
University of MichiganUniversity of MichiganNational Cancer Institute (NCI)National Cancer Institute (NCI)National Institutes of Health (NIH)National Institutes of Health (NIH)United States Department of Health and Human Services (HHS)United States Department of Health and Human Services (HHS)
Clinical Trial
Clinical Trial IDNCT03762135Start Date2020-01-01Completion Date0030-10-30PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
The goal of this study is to test whether the mobile application (app.) helps adolescents make healthy food choices, decreasing calories purchased from restaurants, fewer number of visits to restaurants, and if it has an impact on their body mass index (BMI). Eligible adolescents will be enrolled in the study along with a parent for approximately 6 months.
University of MichiganUniversity of MichiganNational Institute on Minority Health and Health Disparities (NIMHD)National Institute on Minority Health and Health Disparities (NIMHD)National Institutes of Health (NIH)National Institutes of Health (NIH)United States Department of Health and Human Services (HHS)United States Department of Health and Human Services (HHS)
Clinical Trial
Clinical Trial IDNCT04087798Start Date2020-01-01Completion Date2022-06-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
Chronic kidney disease (CKD) is a serious and growing public health problem. The purpose of this study is to find out if an educational worksheet, called the Encounter Decision Intervention (EDI), combined with health coaching helps CKD patients improve their blood pressure and other health outcomes. The research team hypothesizes that the intervention group will have greater improvement in CKD outcomes than the control group.
University of MichiganUniversity of MichiganNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)National Institutes of Health (NIH)National Institutes of Health (NIH)United States Department of Health and Human Services (HHS)United States Department of Health and Human Services (HHS)
Clinical Trial
Clinical Trial IDNCT04070105Start Date2020-01-01Completion Date2022-07-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
A prosthesis that requires no power, yet has the functionality to perform various tasks, including those needed in the military, is extremely important. To bridge the gap between passive and powered prostheses, this study will test the Compliant Adaptive Energy Storage and Return (CAESAR) foot. The investigators will test and improve this foot design mechanically, and then test this design on individuals with lower limb amputation in a lab setting. The goal of this project is to develop a pas…
Clinical Trial
Clinical Trial IDNCT04120883Start Date2020-01-01Completion Date2022-10-01PhasePhase 1/Phase 2Study TypeInterventionalStatusNot yet recruiting
This research study is being done to learn what effect 12 months of treatment with oral hydroxychloroquine (HCQ) will have on the retina in people with retinitis pigmentosa (RP). The hypothesis is that treatment with HCQ is safe and tolerable in patients with autosomal dominant retinitis pigmentosa (adRP) caused by P23H-RHO, and may arrest progression of retinal degeneration by altering the autophagy pathway in photoreceptors. Participants that meet eligibility and agree to the study will be …
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