Clinical Trial IDNCT04157296
Lead SponsorUniversity of Michigan
Principal Investigator
Start Date0004-01-30
Completion Date2021-02-01
Study TypeInterventional
PhaseN/A
StatusRecruiting

Purpose

This study will assign eighteen participants with anxiety to cognitive behavioral therapy (CBT) with computerized cognitive training (CCT). In addition, the study will have a control group and enroll thirty-six age- and gender-matched anxious children assigned to CBT. The hypothesis of this trial is that CCT with CBT will further increase task control network (TCN) activation and connectivity. Both groups will have one CBT therapy session each week for 12 weeks. However, for participants in the CCT arm plus CBT they will also receive up to 4 weeks of at home CCT to complete during the two weeks prior to the first CBT session and during the two weeks after the first CBT session. CCT is to be done at home for approximately 30 minutes per day, 5 days per week. Additionally, participants in the CCT arm plus CBT will receive CCT for 30 minutes just prior to CBT sessions 4-12. Each group will also have pre and post therapy functional magnetic resonance imaging (fMRI) and be asked to complete anxiety severity interviews and questionnaires throughout the study as well as after the treatment.

Conditions

ConditionInterventionPhase
Anxiety DisordersBehavioral: Cognitive behavioral therapy (CBT), Behavioral: computerized cognitive training (CCT)N/A

Eligibility

AgeGenderAccepts Healthy Volunteers
7 Years to 17 YearsAllNo