Clinical Trial IDNCT03452267
Lead SponsorWayne State University
Principal Investigator
  • Kyle Jon Burghardt
Start Date2020-06-01
Completion Date2025-06-01
Study TypeInterventional
PhasePhase 2/Phase 3
StatusNot yet recruiting


The insulin sensitizing effects of metformin and pioglitazone in the skeletal muscle remain unknown. Our group aims to analyze molecular changes within the skeletal muscle of pre-diabetic patients through the use of a clinical trial in humans.


Insulin SensitivityDrug: Metformin, Drug: Pioglitazone, Drug: PlaceboPhase 2/Phase 3


AgeGenderAccepts Healthy Volunteers
18 Years to 60 YearsAllNo